The present study specially aim to study spectrophotometerically the water quality of river Tamsa flowing from the heart of Azamgarh city. In the river Tamsa direct wastes like municipal garbage, sewage as well as industrial wastes is dumped without treatment. River Tamsa is continuously been contaminated by the sewage and other types of wastes. In the present study three parameters were chosen viz. iron, nitrate and phosphate. Although river water of Tamsa would contain appreciable amount of iron, nitrate and phosphate. This study revealed that there is marked variation in the levels of these parameters during the years of study 2009, 2010 and 2011, sometimes it has been found to be more than WHO maximum contamination level.